GTS-21 (DMXB-A)
3-(2,4-dimethoxybenzylidene)anabaseine
CAS: 156223-05-1
Molecular Formula: C19H22Cl2N2O2
GTS-21 (DMXB-A) - Names and Identifiers
GTS-21 (DMXB-A) - Physico-chemical Properties
| Molecular Formula | C19H22Cl2N2O2 |
| Melting Point | 216-217℃ (decomposition) |
| Solubility | H2O: >5mg/mL |
| Appearance | powder |
| Color | faint yellow to dark yellow |
| Storage Condition | 2-8°C |
| In vitro study | GTS-21 bound to human α4β2 nAChR (K i =20 nM) 100-fold more potently than to humanα7-nAChR, and is 18- and 2-fold less potent than (-)-nicotine at human α4β2 and a7 nAChR, respectively. |
| In vivo study | GTS 21 (4 mg/kg; i.p.; 1, 3, 7, 14 and 21 days) reduces radiation induced histological signs of pulmonary injury. Animal Model: C57BL6 mice were irradiated with 12 Gy to induce a mouse model of Radiation induced lung injury (RILI) Dosage: 4 mg/kg Administration: I.p.; 1, 3, 7, 14 and 21 days Result: Reduces lung inflammatory infiltrate and fibrosis in radiation treated mice. |
GTS-21 (DMXB-A) - Risk and Safety
| WGK Germany | 3 |
| RTECS | DW1764860 |
GTS-21 (DMXB-A) - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.623 ml | 13.113 ml | 26.226 ml |
| 5 mM | 0.525 ml | 2.623 ml | 5.245 ml |
| 10 mM | 0.262 ml | 1.311 ml | 2.623 ml |
| 5 mM | 0.052 ml | 0.262 ml | 0.525 ml |
Last Update：2024-01-02 23:10:35
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Product Name: (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridinedihydrochloride Request for quotationCAS: 156223-05-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
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Multiple Specifications
Product Name: 3-(2,4-dimethoxybenzylidene)anabaseine Request for quotationCAS: 156223-05-1
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
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Product Name: 3-(2,4-dimethoxybenzylidene)anabaseine Visit Supplier Webpage Request for quotationCAS: 156223-05-1
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Spot supply
Product Name: DMXB-A; DMBX-anabaseine Visit Supplier Webpage Request for quotationCAS: 156223-05-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
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Product Name: GTS-21 dihydrochloride Visit Supplier Webpage Request for quotationCAS: 156223-05-1
Tel: +16314854226
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View History
GTS-21 (DMXB-A)
福馬酸
2-ETHYLIMIDAZOLINE
Pfu酶
potassium dodecy phosphate
A cyanuric acid chloride ju
Iron powder
CI 77492
福馬酸
2-ETHYLIMIDAZOLINE
Pfu酶
potassium dodecy phosphate
A cyanuric acid chloride ju
Iron powder
CI 77492